Integrated Serologic Surveillance of Population Immunity and Disease Transmission.

ABSTRACT: Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus, but broader testing of existing serologic surveys with multiplex antibody assays would create new opportunities for integrated surveillance. In this perspective, we highlight multiple areas for potential synergy where integrated surveillance could add more value to public health efforts than the current trend of independent disease monitoring through vertical programs. We describe innovations in laboratory and data science that should accelerate integration and identify remaining challenges with respect to specimen collection, testing, and

SUBMITTER: Arnold BF 

PROVIDER: S-EPMC6038749 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature