Prevalence of chronic comorbidities in dengue fever and West Nile virus: A systematic review and meta-analysis.

ABSTRACT:

Background

Flavivirus diseases such as dengue fever (DENV), West Nile virus (WNV), Zika and yellow fever represent a substantial global public health concern. Preexisting chronic conditions such as cardiovascular diseases, diabetes, obesity, and asthma were thought to predict risk of progression to severe infections.

Objective

We aimed to quantify the frequency of chronic comorbidities in flavivirus diseases to provide an estimate for their prevalence in severe and non-severe infections and examine whether chronic diseases contribute to the increased risk of severe viral expression.

Methods

We conducted a comprehensive search in PubMed, Ovid MEDLINE(R), Embase and Embase Classic and grey literature databases to identify studies reporting prevalence estimates of comorb

SUBMITTER: Badawi A 

PROVIDER: S-EPMC6039036 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature