Reconfiguration of a Multi-oscillator Network by Light in the Drosophila Circadian Clock.

ABSTRACT: The brain clock that drives circadian rhythms of locomotor activity relies on a multi-oscillator neuronal network. In addition to synchronizing the clock with day-night cycles, light also reformats the clock-driven daily activity pattern. How changes in lighting conditions modify the contribution of the different oscillators to remodel the daily activity pattern remains largely unknown. Our data in Drosophila indicate that light readjusts the interactions between oscillators through two different modes. We show that a morning s-LNv > DN1p circuit works in series, whereas two parallel evening circuits are contributed by LNds and other DN1ps. Based on the photic context, the master pacemaker in the s-LNv neurons swaps its enslaved partner-oscillator-LNd in the presence of light or DN1p in th

SUBMITTER: Chatterjee A 

PROVIDER: S-EPMC6039274 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature