Comparative Genomic Analysis of 130 Bacteriophages Infecting Bacteria in the Genus Pseudomonas.

ABSTRACT: Bacteria of the genus Pseudomonas are genetically diverse and ubiquitous in the environment. Like other bacteria, those of the genus Pseudomonas are susceptible to bacteriophages which can significantly affect their host in many ways, ranging from cell lysis to major changes in morphology and virulence. Insights into phage genomes, evolution, and functional relationships with their hosts have the potential to contribute to a broader understanding of Pseudomonas biology, and the development of novel phage therapy strategies. Here we provide a broad-based comparative and evolutionary analysis of 130 complete Pseudomonas phage genome sequences available in online databases. We discovered extensive variation in genome size (ranging from 3 to 316 kb), G + C percentag

SUBMITTER: Ha AD 

PROVIDER: S-EPMC6039544 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature