Accuracy of a nomogram to predict the survival benefit of surgical axillary staging in T1 breast cancer patients.

ABSTRACT: T1 breast cancer patients have favorable clinical outcomes, so that whether axillary stating (AS) surgery can be omitted in these patients is still unclear. This retrospective cohort study developed a nomogram to predict the cancer-specific survival (CSS) of T1 breast cancer patients with and without AS and estimate the survival benefit of AS in these patients.We used surveillance, epidemiology, and end results (SEER) database to identify 232,195 breast cancer patients with T1 tumors diagnosed between 1990 and 2008. In the training cohort, we used the Kaplan-Meier method and the competing risk analysis, with non-CSS as the competing risk, to screen for prognostic factors for CSS. A nomogram to predict the CSS, with receiving AS or not as one of the predictors, was developed and externally

SUBMITTER: Chen Y 

PROVIDER: S-EPMC6039583 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature