Corneal infiltration and xanthoma formation in mycosis fungoides.

ABSTRACT:

Purpose

To report a case of corneal infiltration and xanthoma formation in mycosis fungoides (cutaneous T-cell lymphoma).

Observations

A middle aged Japanese man with mycosis fungoides (MF) involving the face was referred to Ophthalmology for evaluation of unilateral, painless conjunctival injection. Biopsy of the conjunctiva revealed a malignant T cell population consistent with MF tumor invasion. Years later, he returned following several episodes of infectious keratitis with a painless, yellow, rapidly forming mass in the left eye over two weeks. Corneal biopsy showed foamy histiocytes and positive staining for CD68, and a diagnosis of corneal xanthoma was made.

Conclusions and importance

Severe ocular surface disease can rarely occur in MF by direct invasion of tu

SUBMITTER: Busch C 

PROVIDER: S-EPMC6040233 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature