RutA-Catalyzed Oxidative Cleavage of the Uracil Amide Involves Formation of a Flavin-N5-oxide.

ABSTRACT: RutA is a novel flavoenzyme on the uracil catabolic pathway that catalyzes uracil ring opening by a unique amide oxidation reaction. Here we provide evidence that this reaction also involves the formation of a flavin-N5-oxide.

SUBMITTER: Adak S 

PROVIDER: S-EPMC6040642 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature