Biomarkers and predictors for functional and anatomic outcomes for small gauge pars plana vitrectomy and peeling of the internal limiting membrane in naive diabetic macular edema: The VITAL Study.

ABSTRACT:

Purpose

We aimed to investigate biomarkers and predictive factors for visual and anatomical outcome in patients with naïve diabetic macular edema (DME) who underwent small gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling as a first line treatment.

Design

Multicenter, retrospective, interventional study.

Participants

120 eyes from 120 patients with naïve DME treated with PPV and ILM peeling with a follow up of 24 months.

Methods

Change in baseline best corrected visual acuity (BCVA) and central subfoveal thickness (CST) 1, 6, 12 and 24 months after surgery. Predictive value of baseline BCVA, CST, optical coherence tomography (OCT) features (presence of subretinal fluid (SRF) and photoreceptor damage), and time between DME diagnosis

SUBMITTER: Iglicki M 

PROVIDER: S-EPMC6040739 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature