Neurite architecture of the planum temporale predicts neurophysiological processing of auditory speech.

ABSTRACT: The left hemispheric advantage in speech perception is reflected in faster neurophysiological processing. On the basis of postmortem data, it has been suggested that asymmetries in the organization of the intrinsic microcircuitry of the posterior temporal lobe may produce this leftward timing advantage. However, whether this hypothetical structure-function relationship exists in vivo has never been empirically validated. To test this assumption, we used in vivo neurite orientation dispersion and density imaging to quantify microcircuitry in terms of axon and dendrite complexity of the left and right planum temporale in 98 individuals. We found that a higher density of dendrites and axons in the temporal speech area is associated with faster neurophysiological processing of auditory speech,

SUBMITTER: Ocklenburg S 

PROVIDER: S-EPMC6040861 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature