3D-specific absorption rate estimation from high-intensity focused ultrasound sonications using the Green's function heat kernel.

ABSTRACT:

Purpose

To evaluate a numerical inverse Green's function method for deriving specific absorption rates (SARs) from high-intensity focused ultrasound (HIFU) sonications using tissue parameters (thermal conductivity, specific heat capacity, and mass density) and three-dimensional (3D) magnetic resonance imaging (MRI) temperature measurements.

Methods

SAR estimates were evaluated using simulations and MR temperature measurements from HIFU sonications. For simulations, a "true" SAR was calculated using the hybrid angular spectrum method for ultrasound simulations. This "true" SAR was plugged into a Pennes bioheat transfer equation (PBTE) solver to provide simulated temperature maps, which were then used to calculate the SAR estimate using the presented method. Zero mean Gaussian

SUBMITTER: Freeman NJ 

PROVIDER: S-EPMC6041163 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature