The neuropsychological profiles and semantic-critical regions of right semantic dementia.

ABSTRACT:

Introduction

Previous literature has revealed that the anterior temporal lobe (ATL) is the semantic hub of left-sided or mixed semantic dementia (SD), whilst the semantic hub of right-sided SD has not been examined.

Methods

Seventeen patients with right-sided SD, 18 patients with left-sided SD and 20 normal controls (NC) underwent neuropsychological assessments and magnetic resonance imaging scans. We investigated the relationship between the degree of cerebral atrophy in the whole brain and the severity of semantic deficits in left and right-sided SD samples, respectively.

Results

We found the semantic deficits of right-sided SD patients were related to bilateral fusiform gyri and left temporal pole, whilst the left fusiform gyrus correlated with the semantic perform

SUBMITTER: Chen K 

PROVIDER: S-EPMC6041419 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature