Virtual localization of the seizure onset zone: Using non-invasive MEG virtual electrodes at stereo-EEG electrode locations in refractory epilepsy patients.

ABSTRACT: In some patients with medically refractory epilepsy, EEG with intracerebrally placed electrodes (stereo-electroencephalography, SEEG) is needed to locate the seizure onset zone (SOZ) for successful epilepsy surgery. SEEG has limitations and entails risk of complications because of its invasive character. Non-invasive magnetoencephalography virtual electrodes (MEG-VEs) may overcome SEEG limitations and optimize electrode placement making SOZ localization safer. Our purpose was to assess whether interictal activity measured by MEG-VEs and SEEG at identical anatomical locations were comparable, and whether MEG-VEs activity properties could determine the location of a later resected brain area (RA) as an approximation of the SOZ. We analyzed data from nine patients who underwent MEG and SEEG e

SUBMITTER: Juarez-Martinez EL 

PROVIDER: S-EPMC6041424 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature