PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix.

ABSTRACT:

Summary

Transcription factors regulate gene expression by binding to specific short DNA sequences of 5-20 bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-resident genomes for matches to a user-supplied PWM or transcription factor binding site model from a public database.

Availability and implementation

The web server and source code are available at http://ccg.vital-it.ch/pwmscan and https://sourceforge.net/projects/pwmscan, respectively.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Ambrosini G 

PROVIDER: S-EPMC6041753 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature