Primary invasive laryngeal mycosis in an immunocompetent patient: a case report and clinico-epidemiological update.

ABSTRACT:

Background

Laryngeal aspergillosis is uncommon and is usually secondary to pulmonary involvement in immunocompromised patients. Primary laryngeal aspergillosis in immunocompetent individuals is extremely rare, with a few cases documented over the last five decades.

Case presentation

We report a case of primary localised laryngeal aspergillosis in a 21-year-old apparently immunocompetent student. Septate hyphae were observed on histopathology of the laryngeal lesion, which was further confirmed as Aspergillus fumigatus after extraction of fungal DNA from formalin fixed paraffin embedded tissue (FFPET) and sequencing. The patient responded well to oral itraconazole therapy over a month.

Conclusions

Since last few decades, cases of primary laryngeal aspergillosis in immu

SUBMITTER: Subramanya SH 

PROVIDER: S-EPMC6042277 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature