Comparative genomic analysis of Enterococcus faecalis: insights into their environmental adaptations.

ABSTRACT:

Background

Enterococcus faecalis is widely studied as a common gut commensal and a nosocomial pathogen. In fact, Enterococcus faecalis is ubiquitous in nature, and it has been isolated from various niches, including the gastrointestinal tract, faeces, blood, urine, water, and fermented foods (such as dairy products). In order to elucidate the role of habitat in shaping the genome of Enterococcus faecalis, we performed a comparative genomic analysis of 78 strains of various origins.

Results

Although no correlation was found between the strain isolation habitat and the phylogeny of Enterococcus faecalis from our whole genome-based phylogenetic analysis, our results revealed some environment-associated features in the analysed Enterococcus faecalis genomes. Significant differen

SUBMITTER: He Q 

PROVIDER: S-EPMC6042284 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature