Predictors of consent to cell line creation and immortalisation in a South African schizophrenia genomics study.

ABSTRACT:

Background

Cell line immortalisation is a growing component of African genomics research and biobanking. However, little is known about the factors influencing consent to cell line creation and immortalisation in African research settings. We contribute to addressing this gap by exploring three questions in a sample of Xhosa participants recruited for a South African psychiatric genomics study: First, what proportion of participants consented to cell line storage? Second, what were predictors of this consent? Third, what questions were raised by participants during this consent process?

Methods

760 Xhose people with schizophrenia and 760 controls were matched to sex, age, level of education and recruitment region. We used descriptive statistics to determine the proportion of

SUBMITTER: Campbell MM 

PROVIDER: S-EPMC6042361 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature