Analysis of cross-population differentiation between Thoroughbred and Jeju horses.

ABSTRACT:

Objective

This study was intended to identify genes positively selected in Thoroughbred horses (THBs) that potentially contribute to their running performances.

Methods

The genomes of THB and Jeju horses (JH, Korean native horse) were compared to identify genes positively selected in THB. We performed cross-population extended haplotype homozygosity (XP-EHH) and cross-population composite likelihood ratio test (XP-CLR) statistical methods for our analysis using whole genome resequencing data of 14 THB and 6 JH.

Results

We identified 98 (XP-EHH) and 200 (XP-CLR) genes that are under positive selection in THB. Gene enrichment analysis identified 72 gene ontology biological process (GO BP) terms. The genes and GO BP terms explained some of THB's characteristics such as i

SUBMITTER: Lee W 

PROVIDER: S-EPMC6043458 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature