Laboratory evaluation of the efficacy and speed of kill of lotilaner (Credelio^TM) against Ixodes ricinus ticks on cats.

ABSTRACT:

Background

Lotilaner, approved for dogs as a chewable tablet formulation, has separately been developed for oral use in cats (Credelio^TM chewable tablets for cats), to meet the need for an easy to use, safe and rapidly effective parasiticide. It is a valid cat- and owner-friendly alternative to topical products. This manuscript describes three pivotal laboratory studies assessing the efficacy and speed of kill of lotilaner in cats against Ixodes ricinus ticks following a single oral administration, at a dose rate close to 6 mg/kg.

Methods

In Studies 1 and 2, efficacy and safety were evaluated 48 h after treatment and post-treatment weekly infestations in 16 cats, against untreated controls, for 35 days. In Study 3, efficacy and safety were assessed in 8 lotilaner-

SUBMITTER: Cavalleri D 

PROVIDER: S-EPMC6044019 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature