Ontology highlight
ABSTRACT:
SUBMITTER: Yan W
PROVIDER: S-EPMC6044186 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Yan Wenjing W Rangaprakash D D Deshpande Gopikrishna G
NeuroImage. Clinical 20180413
Functional MRI (fMRI) is modeled as a convolution of the hemodynamic response function (HRF) and an unmeasured latent neural signal. However, HRF itself is variable across brain regions and subjects. This variability is induced by both neural and non-neural factors. Aberrations in underlying neurochemical mechanisms, which control HRF shape, have been reported in autism spectrum disorders (ASD). Therefore, we hypothesized that this will lead to voxel-specific, yet systematic differences in HRF s ...[more]