The Revised National Alzheimer's Coordinating Center's Neuropathology Form-Available Data and New Analyses.

ABSTRACT: Neuropathologic evaluation remains the gold standard for determining the presence and severity of aging-related neurodegenerative diseases. Researchers at U.S. Alzheimer's Disease Centers (ADCs) have worked for >30 years studying human brains, with the goals of achieving new research breakthroughs. Harmonization and sharing among the 39 current and past ADCs is promoted by the National Alzheimer's Coordinating Center (NACC), which collects, audits, and disburses ADC-derived data to investigators on request. The past decades have witnessed revised disease definitions paired with dramatic expansion in the granularity and multimodality of the collected data. The NACC database now includes cognitive test scores, comorbidities, drug history, neuroimaging, and links to genomics. Relatively, rece

SUBMITTER: Besser LM 

PROVIDER: S-EPMC6044344 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature