Repetition Suppression and Memory for Faces is Reduced in Adults with Autism Spectrum Conditions.

ABSTRACT: Autism spectrum conditions (ASC) are associated with a number of atypicalities in face processing, including difficulties in face memory. However, the neural mechanisms underlying this difficulty are unclear. In neurotypical individuals, repeated presentation of the same face is associated with a reduction in activity, known as repetition suppression (RS), in the fusiform face area (FFA). However, to date, no studies have investigated RS to faces in individuals with ASC, or the relationship between RS and face memory. Here, we measured RS to faces and geometric shapes in individuals with a clinical diagnosis of an ASC and in age and IQ matched controls. Relative to controls, the ASC group showed reduced RS to faces in bilateral FFA and reduced performance on a standardized test of face mem

SUBMITTER: Ewbank MP 

PROVIDER: S-EPMC6044360 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature