Electrochemical Determination of the Serotonin Reuptake Inhibitor, Dapoxetine, Using Cesium-Gold Nanoparticles.

ABSTRACT: Cesium-gold (Cs-Au) nanoparticles are shown to be analytically advantageous for the electroanalytical sensing of dapoxetine (DPX), a serotonin reuptake inhibitor used for the treatment of premature ejaculation. The Cs-Au nanoparticles are electrically wired and supported upon mass producible, economical screen-printed electrochemical sensing platforms and are characterized electrochemically (cyclic voltammetry and electrochemical impedance spectroscopy) and physiochemically (field emission scanning electron microscopy and energy dispersive X-ray analysis). The face-centered design was applied to optimize the significant experimental factors by using square wave voltammetry. The Cs-Au-based sensor is found to exhibit a large linear range (10^-7 to 10^-4 M) with a good an

SUBMITTER: Mohamed MA 

PROVIDER: S-EPMC6044806 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature