Comparison of magnetic resonance angiography and ¹⁸F-fluorodeoxyglucose positron emission tomography in large-vessel vasculitis.

ABSTRACT:

Objectives

To assess agreement between interpretation of magnetic resonance angiography (MRA) and ¹⁸F-fluorodeoxyglucose positron emission tomography (PET) for disease extent and disease activity in large-vessel vasculitis (LVV) and determine associations between imaging and clinical assessments.

Methods

Patients with giant cell arteritis (GCA), Takayasu's arteritis (TAK) and comparators were recruited into a prospective, observational cohort. Imaging and clinical assessments were performed concurrently, blinded to each other. Agreement was assessed by per cent agreement, Cohen's kappa and McNemar's test. Multivariable logistic regression identified MRA features associated with PET scan activity.

Results

Eighty-four patients (GCA=35; TAK=30; comparator=19)

SUBMITTER: Quinn KA 

PROVIDER: S-EPMC6045453 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature