Long-term in vivo biodistribution and toxicity study of functionalized near-infrared persistent luminescence nanoparticles.

ABSTRACT: Near-infrared (NIR) persistent luminescence nanoparticles (NPLNPs) have become one of the most promising candidates for bioimaging. Different from the other fluorescence nanoprobes, the NIR persistent luminescence of NPLNPs can last for a long time after excitation, double exposure that is nanoparticles and light exist during the long-term bioimaging. However, to date, the potential risk of nanoparticles and NIR persistent luminescence of NPLNPs is still unknown. In this study, Cr3 + -doped zinc gallate, Zn_1.1Ga_1.8Sn_0.1O₄:Cr³⁺ (ZGO), the most promising NPLNPs in bioimaging, was chosen as a representative for potential risk assessment. We evaluated the potential risk of nanoparticles and NIR persistent luminescence of ZGO for a long per

SUBMITTER: Sun X 

PROVIDER: S-EPMC6045641 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature