Antacid therapy for gastroesophageal reflux in preterm infants: a systematic review.

ABSTRACT:

Background

Gastro-oesophageal reflux is prevalent in preterm infants. Despite widespread use in clinical practice, there is still much controversy over the efficacy and safety of drug interventions, particularly antacid therapy.

Objective

To systematically review the effects of antacid therapy on preterm infants with symptoms of gastro-oesophageal reflux, and to assess the safety of these interventions.

Methods

We carried out an electronic search of the Cochrane central register of controlled trials (CENTRAL, The Cochrane Library), MEDLINE (1966-present), EMBASE (1980-present) and CINAHL (1982-present) as well as other online sources. Participants were preterm infants (<37 weeks gestation) with gastro-oesophageal reflux disease who were receiving care on a neonatal un

SUBMITTER: Dermyshi E 

PROVIDER: S-EPMC6045735 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature