Anthropometric and blood parameters for the prediction of NAFLD among overweight and obese adults.

ABSTRACT:

Backround

Non-alcoholic fatty liver disease (NAFLD) comprises non-progressive steatosis and non-alcoholic steatohepatitis (NASH), the latter of which may cause cirrhosis and hepatocellular carcinoma (HCC). As NAFLD detection is imperative for the prevention of its complications, we evaluated whether a combination of blood-based biomarkers and anthropometric parameters can be used to predict NAFLD among overweight and obese adults.

Methods

143 overweight or obese non-smokers free of diabetes (50% women, age: 35-65 years) were recruited. Anthropometric indices and routine biomarkers of metabolism and liver function were measured to predict magnetic resonance (MR) - derived NAFLD by multivariable logistic regression models. In addition, we evaluated to which degree the use of m

SUBMITTER: Kuhn T 

PROVIDER: S-EPMC6045848 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature