Connectivity dynamics in typical development and its relationship to autistic traits and autism spectrum disorder.

ABSTRACT: Recent advances in neuroimaging techniques have provided significant insights into developmental trajectories of human brain function. Characterizations of typical neurodevelopment provide a framework for understanding altered neurodevelopment, including differences in brain function related to developmental disorders and psychopathology. Historically, most functional connectivity studies of typical and atypical development operate under the assumption that connectivity remains static over time. We hypothesized that relaxing stationarity assumptions would reveal novel features of both typical brain development related to children on the autism spectrum. We employed a "chronnectomic" (recurring, time-varying patterns of connectivity) approach to evaluate transient states of connectivity usi

SUBMITTER: Rashid B 

PROVIDER: S-EPMC6045960 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature