Patterns of triclosan resistance in Vibrionaceae.

ABSTRACT: The antimicrobial additive triclosan has been used in personal care products widely across the globe for decades. Triclosan resistance has been noted among Vibrio spp., but reports have been anecdotal and the extent of phenotypic triclosan resistance across the Vibrionaceae family has not been established. Here, triclosan resistance was determined for Vibrionaceae strains across nine distinct clades. Minimum inhibitory concentrations (MIC) were determined for 70 isolates from clinical (n = 6) and environmental sources (n = 64); only two were susceptible to triclosan. The mean MIC for all resistant Vibrionaceae was 53 µg mL^-1 (range 3.1-550 µg mL^-1), but was significantly different between clades (p < 0.001). The highest mean triclosa

SUBMITTER: Lydon KA 

PROVIDER: S-EPMC6046194 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature