Patterns of antidepressant use during pregnancy: a nationwide population-based cohort study.

ABSTRACT:

Aims

We explored the patterns of antidepressant use during pregnancy.

Methods

A cohort of women who started a pregnancy in 2014 was identified using data from the French reimbursement healthcare system (covering approximately 99% of the population). Antidepressant usage (initiated before or during pregnancy) was assessed. Explored changes in antidepressant treatment were: associations, switches, discontinuation and resumption of antidepressants during pregnancy.

Results

The cohort included 766 508 pregnancies (755 519 women). Antidepressant use during pregnancy was 25.7 per 1000 [95% CI: 25.3-26.0]. New use concerned 3.9 per 1000 [95% CI: 3.7-4.0]; the most initiated class during pregnancy was selective serotonin reuptake inhibitors (SSRIs), while the most prescribed

SUBMITTER: Benard-Laribiere A 

PROVIDER: S-EPMC6046485 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature