Impairment of decision-making in multiple sclerosis: A neuroeconomic approach.

ABSTRACT:

Objective

To assess the decision-making impairment in patients with multiple sclerosis (MS) and how they relate to other cognitive domains.

Methods

We performed a cross-sectional analysis in 84 patients with MS, and 21 matched healthy controls using four tasks taken from behavioral economics: (1) risk preferences, (2) choice consistency, (3) delay of gratification, and (4) rate of learning. All tasks were conducted using real-world reward outcomes (food or money) in different real-life conditions. Participants underwent cognitive examination using the Brief Repeatable Battery-Neuropsychology.

Results

Patients showed higher risk aversion (general propensity to choose the lottery was 0.51 vs 0.64, p = 0.009), a trend to choose more immediate rewards over larger but dela

SUBMITTER: Sepulveda M 

PROVIDER: S-EPMC6047072 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature