Hypothermia for perinatal asphyxia: trial-based quality of life at 6-7 years.

ABSTRACT:

Objective

To assess the impact of hypothermic neural rescue at birth on health-related quality of life (HRQL) in middle childhood.

Design

Six-year to 7-year follow-up of surviving children from the Total Body Hypothermia for Neonatal Encephalopathy (TOBY) Trial.

Setting

Community study including a single parental questionnaire to collect information on children's HRQL.

Patients

145 children (70 in the control group, 75 in the hypothermia group) whose parents consented and returned the questionnaire.

Interventions

Intensive care with cooling of the body to 33.5°C for 72 hours or intensive care alone.

Main outcome measures

HRQL attributes and utility scores using the Health Utilities Index (HUI).

Results

At 6-7 years, speech appeared dispropo

SUBMITTER: Campbell H 

PROVIDER: S-EPMC6047162 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature