Methods to identify and prioritize patient-centered outcomes for use in comparative effectiveness research.

ABSTRACT:

Background

We used various methods for identifying and prioritizing patient-centered outcomes (PCOs) for comparative effectiveness research (CER).

Methods

We considered potential PCOs ("benefits" and "harms") related to (1) gabapentin for neuropathic pain and (2) quetiapine for bipolar depression. Part 1 (April 2014 to March 2015): we searched for PCO research and core outcome sets (COSs). We conducted electronic searches of bibliographic databases and key websites and examined FDA prescribing information and reports of clinical trials and systematic reviews. We asked patient and clinician co-investigators to identify PCOs. Part 2 (not part of our original study protocol): in 2015, we surveyed members of The TMJ Association, Ltd., a patient group associated with temporomandi

SUBMITTER: Mayo-Wilson E 

PROVIDER: S-EPMC6047482 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature