A unique increase in prefrontal gray matter volume in hoarding disorder compared to obsessive-compulsive disorder.

ABSTRACT:

Background

Hoarding disorder (HD) is a disease concept newly presented in DSM-5. As far as we know, no studies have examined the structural changes relevant to hoarding by applying the diagnostic criteria of HD in DSM-5. In the present study, we aimed to find abnormalities in gray matter (GM) structures of patients with HD.

Methods

Seventeen patients who met the DSM-5 criteria for HD, 17 obsessive-compulsive disorder (OCD) patients, and 17 healthy controls (HCs) participated in this study. All participants underwent MRI scanning of the brain by a 3.0-Tesla MRI scanner. In a voxel-based morphometric procedure, preprocessed GM structural images were used to compare the three groups. Thereafter we investigated the correlation between the clinical data (age of onset, symptomatic

SUBMITTER: Yamada S 

PROVIDER: S-EPMC6047811 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature