The murine female intestinal microbiota does not shift throughout the estrous cycle.

ABSTRACT: Pregnancy is accompanied by maternal physiological adaptations including metabolic, endocrine, immune, cardiovascular, skeletomuscular and neurological modifications that facilitate fetal and placental growth and development. Emerging evidence suggests that the maternal intestinal microbiota is modified over the course of healthy pregnancy. We have recently identified a maternal intestinal microbial shift within hours of conception; a shift that continued with advancing gestation. It is possible that maternal gut bacterial profiles might be associated with the known endocrine changes that accompany the female reproductive (estrous) cycle.

Methods

To determine whether the estrous cycle influenced the shifts in the maternal intestinal microbiota, time-matched fecal pellets were collec

SUBMITTER: Wallace JG 

PROVIDER: S-EPMC6047814 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature