Developmental prosopagnosics have widespread selectivity reductions across category-selective visual cortex.

ABSTRACT: Developmental prosopagnosia (DP) is a neurodevelopmental disorder characterized by severe deficits with facial identity recognition. It is unclear which cortical areas contribute to face processing deficits in DP, and no previous studies have investigated whether other category-selective areas function normally in DP. To address these issues, we scanned 22 DPs and 27 controls using a dynamic localizer consisting of video clips of faces, scenes, bodies, objects, and scrambled objects. We then analyzed category selectivity, a measure of the tuning of a cortical area to a particular visual category. DPs exhibited reduced face selectivity in all 12 face areas, and the reductions were significant in three posterior and two anterior areas. DPs and controls showed similar responses to faces in ot

SUBMITTER: Jiahui G 

PROVIDER: S-EPMC6048498 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature