Risk-stratifying capacity of PET/CT metabolic tumor volume in stage IIIA non-small cell lung cancer.

ABSTRACT:

Objectives

Stage IIIA non-small cell lung cancer (NSCLC) is heterogeneous in tumor burden, and its treatment is variable. Whole-body metabolic tumor volume (MTV_WB) has been shown to be an independent prognostic index for overall survival (OS). However, the potential of MTV_WB to risk-stratify stage IIIA NSCLC has previously been unknown. If we can identify subgroups within the stage exhibiting significant OS differences using MTV_WB, MTV_WB may lead to adjustments in patients' risk profile evaluations and may, therefore, influence clinical decision making regarding treatment. We estimated the risk-stratifying capacity of MTV_WB in stage IIIA by comparing OS of stratified stage IIIA with stage IIB and IIIB NSCLC.

Methods

We p

SUBMITTER: Finkle JH 

PROVIDER: S-EPMC6048959 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature