MWASTools: an R/bioconductor package for metabolome-wide association studies.

ABSTRACT:

Summary

MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results.

Availability and implementation

The MWASTools R package is implemented in R (version  > =3.4) and is available from Bioconductor: https://bioconductor.org/packages/MWASTools/.

Contact

[e-mail].

Supplementary information

Supplementary d

SUBMITTER: Rodriguez-Martinez A 

PROVIDER: S-EPMC6049002 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature