Heterogeneity Between States in the Health and Economic Impact of Measles Immunization in the United States.

ABSTRACT:

Background

Vaccines have been used successfully for disease elimination programs in many countries. Evidence on the impact of vaccination programs can support decision-making among medical practitioners and policy makers to improve immunization rates. We estimated the health and economic impact of measles vaccination for each of the 48 contiguous states and the District of Columbia since 1964.

Methods

For each state, we fitted multiple time-series models to prevaccination data and used the best-fitting model to predict counterfactual cases that would have occurred in the absence of vaccination. We then subtracted observed from counterfactual measles cases, deaths, and related costs to estimate the impact of vaccination.

Results

We estimated that 149 million children w

SUBMITTER: Paternina-Caicedo A 

PROVIDER: S-EPMC6049022 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature