Theory, practice, and conservation in the age of genomics: The Galapagos giant tortoise as a case study.

ABSTRACT: High-throughput DNA sequencing allows efficient discovery of thousands of single nucleotide polymorphisms (SNPs) in nonmodel species. Population genetic theory predicts that this large number of independent markers should provide detailed insights into population structure, even when only a few individuals are sampled. Still, sampling design can have a strong impact on such inferences. Here, we use simulations and empirical SNP data to investigate the impacts of sampling design on estimating genetic differentiation among populations that represent three species of Galápagos giant tortoises (Chelonoidis spp.). Though microsatellite and mitochondrial DNA analyses have supported the distinctiveness of these species, a recent study called into question how well these markers matched wit

SUBMITTER: Gaughran SJ 

PROVIDER: S-EPMC6050186 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature