Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study.

ABSTRACT:

Objective

To describe liver disease related mortality in the United States during 1999-2016 by age group, sex, race, cause of liver disease, and geographic region.

Design

Observational cohort study.

Setting

Death certificate data from the Vital Statistics Cooperative, and population data from the US Census Bureau compiled by the Center for Disease Control and Prevention's Wide-ranging Online Data for Epidemiologic Research (1999-2016).

Participants

US residents.

Main outcome measure

Deaths from cirrhosis and hepatocellular carcinoma, with trends evaluated using joinpoint regression.

Results

From 1999 to 2016 in the US annual deaths from cirrhosis increased by 65%, to 34 174, while annual deaths from hepatocellular carcinoma doubled to 11 073. Only

SUBMITTER: Tapper EB 

PROVIDER: S-EPMC6050518 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature