Effect of temperature control on the metabolite content in exhaled breath condensate.

ABSTRACT: The non-invasive, quick, and safe collection of exhaled breath condensate makes it a candidate as a diagnostic matrix in personalized health monitoring devices. The lack of standardization in collection methods and sample analysis is a persistent limitation preventing its practical use. The collection method and hardware design are recognized to significantly affect the metabolomic content of EBC samples, but this has not been systematically studied. Here, we completed a series of experiments to determine the sole effect of collection temperature on the metabolomic content of EBC. Temperature is a likely parameter that can be controlled to standardize among different devices. The study considered six temperature levels covering two physical phases of the sample; liquid and solid. The use o

SUBMITTER: Zamuruyev KO 

PROVIDER: S-EPMC6050983 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature