Radiotherapy vs surgery for T1-2N0M0 laryngeal squamous cell carcinoma: A population-based and propensity score matching study.

ABSTRACT: There are conflicting reports about whether radiotherapy or surgery is optimal for early-stage laryngeal squamous cell carcinoma (LSCC), although both have recently been recommended. Patients with T1-2N0M0 LSCC in the population-based SEER database who underwent radiotherapy or surgery were reviewed. Propensity score matching was used to eliminate the baseline variations. After matching, 1913 pairs of patients were included. Overall, patients who received radiotherapy had worse cancer-specific survival than patients with surgery. After stratification, the survival in patients who received radiotherapy was worse with respect to the following characteristics: ≤60 years of age; T1a glottis cancer; well-differentiated tumors; and with married status. In other patients, survival outcomes were s

SUBMITTER: Zhan C 

PROVIDER: S-EPMC6051150 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature