PATRI, a Genomics Data Integration Tool for Biomarker Discovery.

ABSTRACT: The availability of genomic datasets in association with clinical, phenotypic, and drug sensitivity information represents an invaluable source for potential therapeutic applications, supporting the identification of new drug sensitivity biomarkers and pharmacological targets. Drug discovery and precision oncology can largely benefit from the integration of treatment molecular discriminants obtained from cell line models and clinical tumor samples; however this task demands comprehensive analysis approaches for the discovery of underlying data connections. Here we introduce PATRI (Platform for the Analysis of TRanslational Integrated data), a standalone tool accessible through a user-friendly graphical interface, conceived for the identification of treatment sensitivity biomarkers from use

SUBMITTER: Ukmar G 

PROVIDER: S-EPMC6051285 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature