Decoding moral emotions in obsessive-compulsive disorder.

ABSTRACT:

Background

Patients with obsessive-compulsive disorder (OCD) exhibit abnormal neural responses when they experience particular emotions or when they evaluate stimuli with emotional value. Whether these brain responses are sufficiently distinctive to discriminate between OCD patients and healthy controls is unknown. The present study is the first to investigate the discriminative power of multivariate pattern analysis of regional fMRI responses to moral and non-moral emotions.

Method

To accomplish this goal, we performed a searchlight-based multivariate pattern analysis to unveil brain regions that could discriminate 18 OCD patients from 18 matched healthy controls during provoked guilt, disgust, compassion, and anger. We also investigated the existence of distinctive neural

SUBMITTER: Fontenelle LF 

PROVIDER: S-EPMC6051311 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature