Altered perspective-dependent brain activation while viewing hands and associated imitation difficulties in individuals with autism spectrum disorder.

ABSTRACT:

Background

Individuals with autism spectrum disorder (ASD) appear to have a unique awareness of their own body, which may be associated with difficulties of gestural interaction. In typically developing (TD) individuals, the perception of body parts is processed in various brain regions. For instance, activation of the lateral occipito-temporal cortex (LOTC) is known to depend on perspective (i.e., first- or third-person perspective) and identity (i.e., own vs. another person's body). In the present study, we examined how perspective and identity affect brain activation in individuals with ASD, and how perspective- and identity-dependent brain activation is associated with gestural imitation abilities.

Methods

Eighteen young adults with ASD and 18 TD individuals participated

SUBMITTER: Okamoto Y 

PROVIDER: S-EPMC6051493 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature