Associations between birth characteristics and age-related cognitive impairment and dementia: A registry-based cohort study.

ABSTRACT:

Background

There is evidence for long-lasting effects of birth characteristics on cognitive ability in childhood and adulthood. Further, low cognitive ability throughout the lifetime has been linked to age-related cognitive decline and dementia risk. However, little is known about the effects of birth characteristics on cognitive dysfunction late in life. Here we explore potential associations between birth characteristics (weight, head circumference, length, and gestational age), adjusted and not adjusted for gestational age, and cognitive impairment and dementia late in life.

Methods and findings

Data from twins in the Swedish Twin Registry born 1926-1960 were merged with information from the Swedish birth, patient, and cause of death registries, resulting in a sample of 3

SUBMITTER: Mosing MA 

PROVIDER: S-EPMC6051563 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature