The Cow Milk Symptom Score (CoMiSSTM) in presumed healthy infants.

ABSTRACT:

Objective

The Cow's Milk-related Symptom Score (CoMiSSTM) was developed as an awareness tool to recognize possible manifestations of cow's milk protein allergy (CMPA). Arbitrarily, a cut-off value of ≥12 was defined as a "positive score." The aim of this study was to determine an age-related CoMiSS in healthy infants to minimize the risk of false reassurance or over-diagnosis of CMPA in case of a negative or positive score, respectively.

Methods

General pediatricians determined the CoMiSS in presumed healthy infants aged ≤6 months during a routine visit. Exclusion criteria included any known acute or chronic disease, preterm delivery (< 37 weeks), therapeutic formula, any food supplement (except vitamins) or medication.

Results

Data from 891 consecutive infants were c

SUBMITTER: Vandenplas Y 

PROVIDER: S-EPMC6051613 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature