Age-related macular degeneration and progression of coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Background

Age-related macular degeneration (AMD) shares many similarities with cardiovascular disease (CVD) pathophysiology. We sought to determine the relationship of AMD to the progression of coronary artery calcium (CAC) using data from the Multi-Ethnic Study of Atherosclerosis (MESA).

Methods

Our cohort consisted of 5803 adults aged 45 to 84 years free of known cardiovascular disease (CVD). Retinal photographs were taken during visit 2 (Aug 2002-Jan 2004). CAC was measured with computed tomography at visit 1 (July 2000-Aug 2002) and visit 5 (April 2010-Dec 2011) and changes between visits were determined.

Results

Participants were categorized as with (n = 244) and without AMD (n = 5559) at visit 2. At visit 5, 92 participants with and 2684 without AMD had CAC sco

SUBMITTER: Fernandez AB 

PROVIDER: S-EPMC6051657 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature