Natural menstrual rhythm and oral contraception diversely affect exhaled breath compositions.

ABSTRACT: Natural menstrual cycle and/or oral contraception diversely affect women metabolites. Longitudinal metabolic profiling under constant experimental conditions is thereby realistic to understand such effects. Thus, we investigated volatile organic compounds (VOCs) exhalation throughout menstrual cycles in 24 young and healthy women with- and without oral contraception. Exhaled VOCs were identified and quantified in trace concentrations via high-resolution real-time mass-spectrometry, starting from a menstruation and then repeated follow-up with six intervals including the next bleeding. Repeated measurements within biologically comparable groups were employed under optimized measurement setup. We observed pronounced and substance specific changes in exhaled VOC concentrations throughout all

SUBMITTER: Sukul P 

PROVIDER: S-EPMC6052073 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature