Allergic sensitization and clinical outcomes in urban children with asthma, 2013-2016.

ABSTRACT:

Background

The aim of this study was to examine if food and/or aeroallergen sensitization was associated with worse asthma, pulmonary function tests (PFT), and laboratory markers.

Methods

At our institution, 386 children with asthma were divided into allergic and nonallergic groups based on allergen-specific immunoglobulin E (IgE) testing classes 1-6 versus 0. Asthma severity and/or control, IgE level, eosinophil counts and/or percentages, forced vital capacity (FVC), forced expiratory volume in the first second of expiration (FEV1), and FEV1/FVC, were compared by using bivariate, regression, and subgroup analyses for children who were highly allergic (≥4 allergens).

Results

A total of 291 subjects with asthma were allergic, significantly older, and had higher mean Ig

SUBMITTER: Nagarajan S 

PROVIDER: S-EPMC6052173 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature